Literature summary for 2.1.1.4 extracted from

Konturek, P.C.; Konturek, S.J.; Burnat, G.; Brzozowski, T.; Brzozowska, I.; Reiter, R.J.
Dynamic physiological and molecular changes in gastric ulcer healing achieved by melatonin and its precursor L-tryptophan in rats (2008), J. Pineal Res., 45, 180-190.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
stomach	mucosa from the ulcer margin	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
HIOMT	-	Rattus norvegicus
hydroxyindole-O-methyltransferase	-	Rattus norvegicus

Expression

Organism	Comment	Expression
Rattus norvegicus	the mRNA expression for HIOMT is only slightly increased at day 0 upon ulcer induction when compared with that in the intact mucosa, but at day 8 after ulcer formation, this expression of HIOMT is significantly enhanced, particularly at the ulcer areas in rats treated with melatonin or L-tryptophan	up

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Release 2023.1 (January 2023)