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Literature summary for 2.1.1.4 extracted from
- Photoreceptor-specific expression, light-dependent localization, and transcriptional targets of the zinc-finger protein Yin Yang 1 in the chicken retina (2008), J. Neurochem., 105, 595-604.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in HEK-293 cells | Gallus gallus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| embryo | - |
Gallus gallus | - |
| retina | embryonic retina | Gallus gallus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HIOMT | - |
Gallus gallus |
| hydroxyindole-O-methyltransferase | - |
Gallus gallus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Gallus gallus | In retinal cells the mutation of the YY1-binding site decreases the HIOMT promoter activity by 70% | down |
| Gallus gallus | the rat Crx transcription factor is able to activate the HIOMT promoter in transfected HEK-293 cells | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | last enzyme of the melatonin-synthesis pathway | Gallus gallus |
| physiological function | HIOMT is required for full transcriptional activation in chicken embryonic retinal cells | Gallus gallus |
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Release 2023.1 (January 2023)
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