Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | highest activity in liver | Rattus norvegicus | - |
spleen | lowest activity in spleen | Rattus norvegicus | - |
thymus | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetylserotonin + S-adenosyl-L-methionine | - |
Rattus norvegicus | S-adenosyl-L-homocysteine + N-acetyl-5-methoxytryptamine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HIOMT | - |
Rattus norvegicus |
hydroxyindole-O-methyltransferase | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | there is an age-related decline in rat extrapineal melatonin synthesis with a consequent HIOMT functionality decrease in spleen, liver and heart during physiological aging, in the thymus HIOMT expression reveals no significant alterations with age | down |
General Information | Comment | Organism |
---|---|---|
metabolism | HIOMT is a key enzyms involved in melatonin synthesis | Rattus norvegicus |