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Literature summary for 2.1.1.37 extracted from

  • Siedlecki, P.; Boy, R.G.; Comagic, S.; Schirrmacher, R.; Wiessler, M.; Zielenkiewicz, P.; Suhai, S.; Lyko, F.
    Establishment and functional validation of a structural homology model for human DNA methyltransferase 1 (2003), Biochem. Biophys. Res. Commun., 306, 558-563.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(N4-fluoroacetyl-5-azacytidine) efficient inhibitor of DNA methylation in human tumor cell lines Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P26358
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + DNA
-
Homo sapiens S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine
-
?

Synonyms

Synonyms Comment Organism
DNA methyltransferase 1
-
Homo sapiens
Dnmt1
-
Homo sapiens