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Literature summary for 2.1.1.339 extracted from

  • Nagel, J.; Culley, L.; Lu, Y.; Liu, E.; Matthews, P.; Stevens, J.; Page, J.
    EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyzes the biosynthesis of xanthohumol (2008), Plant Cell, 20, 186-200.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.339

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.019
-
 resveratrol pH 7.5, 30°C Humulus lupulus
0.023
-
 desmethylxanthohumol pH 7.5, 30°C Humulus lupulus
0.031
-
 xanthohumol pH 7.5, 30°C Humulus lupulus
0.034
-
 S-adenosyl-L-methionine pH 7.5, 30°C Humulus lupulus
0.237
-
 chalconaringenin pH 7.5, 30°C Humulus lupulus

Metals/Ions

Metals/Ions Comment Organism Structure
additional information bivalent cations (Mg2+, Fe2+, Zn2+, Cu2+, Ca2+, and Co2+) are not required for activity Humulus lupulus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
64000
-
 gel filtration Humulus lupulus

Organism

Organism UniProt Comment Textmining
Humulus lupulus B0ZB56
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 2',4-dihydroxychalcone 45% of the activity with isoliquiritigenin Humulus lupulus S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + butein 50% of the activity with isoliquiritigenin Humulus lupulus S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + chalconaringenin 40% of the activity with isoliquiritigenin Humulus lupulus S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + desmethylxanthohumol 25% of the activity with isoliquiritigenin Humulus lupulus S-adenosyl-L-homocysteine + 4'-O-methyl-desmethylxanthohumol
-
 ?
S-adenosyl-L-methionine + guaiacol 42% of the activity with isoliquiritigenin Humulus lupulus S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + isoliquiritigenin
-
 Humulus lupulus S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + resveratrol 87% of the activity with isoliquiritigenin Humulus lupulus S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + xanthohumol 36% of the activity with isoliquiritigenin Humulus lupulus S-adenosyl-L-homocysteine + 4'-O-methylxanthohumol
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 39792, calculated Humulus lupulus

Synonyms

Synonyms Comment Organism
OMT2
-
 Humulus lupulus
S-adenosyl-L-methionine-dependent O-methyltransferase
-
 Humulus lupulus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
39
-
-
 Humulus lupulus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
-
 Humulus lupulus