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Literature summary for 2.1.1.232 extracted from

  • Kim, M.; Kim, B.; Ahn, J.
    Biosynthesis of bioactive O-methylated flavonoids in Escherichia coli (2013), Appl. Microbiol. Biotechnol., 97, 7195-7204.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene Os12g0240900, DNA and amino acid sequence determination and analysis, recombinant expression in Escherichia coli, functional coexpression of plant enzymes, e.g. 4-coumaroyl-CoA ligase and chalcone synthase, of different origins catalyzing steps in flavonoid biosynthesis pathways for production of naringenin from p-coumaric acid and synthesis of ponciretin and sakuranetin from naringenin in engineered and transformed Escherichia coli strain BL21(DE3) Oryza sativa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + (2S)-naringenin Oryza sativa reaction of NOMT S-adenosyl-L-homocysteine + (2S)-sakuranetin
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?

Organism

Organism UniProt Comment Textmining
Oryza sativa Q0IP69 cv. Nakdong, gene NOMT-2
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + (2S)-naringenin reaction of NOMT Oryza sativa S-adenosyl-L-homocysteine + (2S)-sakuranetin
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?

Synonyms

Synonyms Comment Organism
naringenin O-methyltransferase
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Oryza sativa
NOMT
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Oryza sativa

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
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Oryza sativa

General Information

General Information Comment Organism
metabolism the enzyme catalyzes the last step in the biosynthesis of the bioactive flavonoid sakuranetin, biosynthetic pathway starting with glucose, overview Oryza sativa