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Literature summary for 2.1.1.21 extracted from

  • Latypova, E.; Yang, S.; Wang, Y.S.; Wang, T.; Chavkin, T.A.; Hackett, M.; Schaefer, H.; Kalyuzhnaya, M.G.
    Genetics of the glutamate-mediated methylamine utilization pathway in the facultative methylotrophic beta-proteobacterium Methyloversatilis universalis FAM5 (2010), Mol. Microbiol., 75, 426-439.
    View publication on PubMed
Search for more literature for 2.1.1.21

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
methylamine + L-glutamate Methyloversatilis universalis
-
 NH3 + N-methyl-L-glutamate
-
 ?
methylamine + L-glutamate Methyloversatilis universalis FAM5
-
 NH3 + N-methyl-L-glutamate
-
 ?

Organism

Organism UniProt Comment Textmining
Methyloversatilis universalis
-
 FAM5
-
Methyloversatilis universalis FAM5
-
 FAM5
-

Purification (Commentary)

Purification (Comment) Organism
cell extracts are prepared Methyloversatilis universalis

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0113
-
 mutant strain NMGP5, protein extract from cells grown on methanol and induced with methylamine Methyloversatilis universalis
0.0118
-
 mutant strain NMGP4, protein extract from cells grown on methanol and induced with methylamine Methyloversatilis universalis
0.0223
-
 wild-type strain, protein extract from cells grown on methanol Methyloversatilis universalis
0.0557
-
 mutant strain NMGP3, protein extract from cells grown on methanol and induced with methylamine Methyloversatilis universalis
0.0705
-
 wild-type strain, protein extract from cells grown on methanol and induced with methylamine Methyloversatilis universalis
0.1113
-
 wild-type strain, protein extract from cells grown on methylamine Methyloversatilis universalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methylamine + L-glutamate
-
 Methyloversatilis universalis NH3 + N-methyl-L-glutamate
-
 ?
methylamine + L-glutamate
-
 Methyloversatilis universalis FAM5 NH3 + N-methyl-L-glutamate
-
 ?

Synonyms

Synonyms Comment Organism
N-methylglutamate synthase
-
 Methyloversatilis universalis
N-methylglutamate synthetase
-
 Methyloversatilis universalis
NMGS
-
 Methyloversatilis universalis