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Literature summary for 2.1.1.20 extracted from
- Characterization of the 5 regulatory region of the human glycine N-methyltransferase gene (2009), Gene, 443, 151-157.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | glycine N-methyltransferase is a tumor susceptibility gene for both hepatocellular carcinoma and prostate cancer | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| nucleus | - |
Homo sapiens | 5634 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HA22T/VGH cell | - |
Homo sapiens | - |
| HEK-293A cell | - |
Homo sapiens | - |
| Hep-G2 cell | - |
Homo sapiens | - |
| HuH-6 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + glycine | - |
Homo sapiens | S-adenosyl-L-homocysteine + N-methylglycine | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GNMT | - |
Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | benzo[a]pyrene treatment of HepG2 cells (0.001 or 0.01 mM) induces GNMT expression | up |
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Release 2023.1 (January 2023)
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