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Literature summary for 2.1.1.20 extracted from

  • Lee, C.M.; Chen, S.Y.; Lee, Y.C.; Huang, C.Y.; Chen, Y.M.
    Benzo[a]pyrene and glycine N-methyltransferse interactions: gene expression profiles of the liver detoxification pathway (2006), Toxicol. Appl. Pharmacol., 214, 126-135.
    View publication on PubMed

Application

Application Comment Organism
medicine GNMT sequesters benzo[a]pyrene, diminishes benzo[a]pyrene's effects to the liver detoxification pathway and prevents subsequent cytotoxicity Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
overexpression of GNMT in SCG2-1-1 cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell expresses very low levels of GNMT Homo sapiens
-
liver
-
Homo sapiens
-
additional information SCG2-1-1 cell, expresses high levels of GNMT Homo sapiens
-

Synonyms

Synonyms Comment Organism
GNMT
-
Homo sapiens