Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Sprague-Dawley rats of 125-149 g. Diabetes and all-trans-retinoic acid administration decrease the hepatic phosphatidylethanolamine:phosphatidylcholine ratio by 37% compared to control values | - |
Source Tissue | Comment | Organism | Textmining |
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liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
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additional information | - |
the activity of phosphatidylethanolamine N-methyltransferase increases (58% higher on day 5, 72% higher on day 7) over 7 d following the injection of streptozotocin (injection of 60 mg/kg on day 0). Diabetes increases the phosphatidylethanolamine N-methyltransferase activity and abundance. Administration of all-trans-retinoic acid alone or in combination with streptozotocin has no effect on phosphatidylethanolamine N-methyltransferase activity. Phosphatidylethanolamine N-methyltransferase activity and abundance in the streptozotocin + insulin group is not significantly different from control values. The enzymatic activity of phosphatidylethanolamine N-methyltransferase is determined by measuring the incorporation of radiolabled methyl groups from S-adenosyl-L-[methyl-3H]methionine into phospholipids. | Rattus norvegicus |
Synonyms | Comment | Organism |
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PEMT | - |
Rattus norvegicus |