Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
Mdr2 (+/-), Mdr2 (+/+) and wild type FVB/NJ female mice, 8-10 weeks old | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
phosphatidylethanolamine N-methyltransferase activity is significantly lower in Mdr2 (+/-) compared to Mdr2 (+/+) mice: 1.20 nmol/mg/min vs. 1.98 nmol/mg/min. After 7 days on methionine and choline deficient diet enzyme activity is: Mdr2 (+/-) = 1.31 nmol/mg/min vs. Mdr2 (+/+) = 1.96 nmol/mg/min. After 30 days on methionine and choline deficient diet enzyme activity is: Mdr2 (+/-) = 1.60 nmol/mg/min vs. Mdr2 (+/+) = 1.99 nmol/mg/min | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mdr2 (+/-) and Mdr2 (+/+) mice have similar S-adenosylmethionine levels at 0 and 7 days on methionine and choline deficient diet, Mdr2 (+/-) mice have significantly higher S-adenosylmethionine levels after 30 days on methionine and choline deficient diet (40.2 vs. 6.1 nmol/g). | Mus musculus | additional information | S-adenosylhomocysteine levels are significantly lower in Mdr2 (+/-) compared to Mdr2 (+/+) mice at 0 days (33.4 vs. 41.9 nmol/g) and 7 days on methionine and choline deficient diet (16.0 vs. 42.9 nmol/g). | ? |
Synonyms | Comment | Organism |
---|---|---|
PEMT | - |
Mus musculus |