Literature summary for 2.1.1.160 extracted from

Mizuno, K.; Matsuzaki, M.; Kanazawa, S.; Tokiwano, T.; Yoshizawa, Y.; Kato, M.
Conversion of nicotinic acid to trigonelline is catalyzed by N-methyltransferase belonged to motif B methyltransferase family in Coffea arabica (2014), Biochem. Biophys. Res. Commun., 452, 1060-1066.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
S-adenosyl-L-methionine + 3,7-dimethylxanthine	Coffea arabica	-	S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine	i.e. caffeine	?

Organism

Organism	UniProt	Comment	Textmining
Coffea arabica	Q8H0D3	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + 3,7-dimethylxanthine	-	Coffea arabica	S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine	i.e. caffeine	?
S-adenosyl-L-methionine + 7-methylxanthine	-	Coffea arabica	S-adenosyl-L-homocysteine + 3,7-dimethylxanthine	i.e. theobromine	?

Synonyms

Synonyms	Comment	Organism
caffeine synthase	-	Coffea arabica
CCS1	-	Coffea arabica

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Release 2023.1 (January 2023)