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Literature summary for 2.1.1.14 extracted from
- Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate (2004), J. Biol. Chem., 279, 44235-44238.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| cocrystallization with L-homocysteine or met and ternary complexes with folate substrates, sitting drop method | Arabidopsis thaliana |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Zinc | His647, Cys649 and Cys733 are involved in zinc coordination. Addition of L-homocysteine leads to reorganization of the zinc binding site with a stronger coordination to Cys649, Cys733, and a water molecule | Arabidopsis thaliana |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AtMetE | - |
Arabidopsis thaliana |
| cobalamin-independent methionine synthase | - |
Arabidopsis thaliana |
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