Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-acetyl-S-farnesyl-L-cysteine methylester | noncompetitive inhibition with respect to biotin-S-farnesyl-L-cysteine, mixed type inhibition with respect to S-adenosyl-L-methionine | Homo sapiens | |
S-adenosyl-L-homocysteine | competitive inhibitor with respect to S-adenosyl-L-methionine | Homo sapiens | |
S-Farnesylthioacetic acid | dead-end inhibitor | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0021 | - |
biotin-S-farnesyl-L-cysteine | - |
Homo sapiens | |
0.0078 | - |
S-adenosyl-L-methionine | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + N-biotinyl-S-farnesyl-L-cysteine | - |
Homo sapiens | S-adenosyl-L-homocysteine + N-biotinyl-S-farnesyl-L-cysteine methyl ester | S-adenosyl-L-homocysteine is the final product released | ? |
Synonyms | Comment | Organism |
---|---|---|
Icmt | - |
Homo sapiens |
isoprenylcysteine carboxylmethyltransferase | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00117 | - |
S-Farnesylthioacetic acid | - |
Homo sapiens | |
0.0021 | - |
N-acetyl-S-farnesyl-L-cysteine methyl ester | with respect to biotin-S-farnesyl-L-cysteine | Homo sapiens | |
0.00243 | - |
N-acetyl-S-farnesyl-L-cysteine methyl ester | with respect to S-adenosyl-L-methionine | Homo sapiens | |
0.00354 | - |
S-adenosyl-L-homocysteine | with respect to S-adenosyl-L-methionine | Homo sapiens | |
0.00359 | - |
S-adenosyl-L-homocysteine | with respect to biotin-S-farnesyl-L-cysteine | Homo sapiens |