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Literature summary for 2.1.1.10 extracted from

  • Shapiro, S.K.; Yphantis, D.A.
    Assay of S-methylmethionine and S-adenosylmethionine homocysteine transmethylases (1959), Biochim. Biophys. Acta, 36, 241-244.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + L-homocysteine Rattus norvegicus
-
S-adenosyl-L-homocysteine + L-methionine
-
?
S-adenosyl-L-methionine + L-homocysteine Saccharomyces cerevisiae
-
S-adenosyl-L-homocysteine + L-methionine
-
?
S-adenosyl-L-methionine + L-homocysteine Klebsiella aerogenes
-
S-adenosyl-L-homocysteine + L-methionine
-
?
S-adenosyl-L-methionine + L-homocysteine Escherichia coli biosynthesis of methionine S-adenosyl-L-homocysteine + L-methionine
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Klebsiella aerogenes
-
-
-
Rattus norvegicus
-
-
-
Saccharomyces cerevisiae
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney low activity Rattus norvegicus
-
liver high activity Rattus norvegicus
-
additional information no activity detected in brain and heart Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0008
-
kidney, S-methyl-L-methionine as methyl donor Rattus norvegicus
0.0022
-
liver, S-adenosyl-L-methionine as methyl donor Rattus norvegicus
0.0087
-
liver, S-methyl-L-methionine as methyl donor Rattus norvegicus
0.012
-
S-methyl-L-methionine as methyl donor Escherichia coli
0.014
-
S-methyl-L-methionine as methyl donor Saccharomyces cerevisiae
0.017
-
S-methyl-L-methionine as methyl donor Klebsiella aerogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + L-homocysteine
-
Escherichia coli S-adenosyl-L-homocysteine + L-methionine
-
?
S-adenosyl-L-methionine + L-homocysteine
-
Rattus norvegicus S-adenosyl-L-homocysteine + L-methionine
-
?
S-adenosyl-L-methionine + L-homocysteine
-
Saccharomyces cerevisiae S-adenosyl-L-homocysteine + L-methionine
-
?
S-adenosyl-L-methionine + L-homocysteine
-
Klebsiella aerogenes S-adenosyl-L-homocysteine + L-methionine
-
?
S-adenosyl-L-methionine + L-homocysteine biosynthesis of methionine Escherichia coli S-adenosyl-L-homocysteine + L-methionine
-
?
S-methyl-L-methionine + L-homocysteine S-methyl-L-methionine more effective methyl donor than S-adenosyl-L-methionine Escherichia coli ?
-
?
S-methyl-L-methionine + L-homocysteine S-methyl-L-methionine more effective methyl donor than S-adenosyl-L-methionine Rattus norvegicus ?
-
?
S-methyl-L-methionine + L-homocysteine S-methyl-L-methionine more effective methyl donor than S-adenosyl-L-methionine Saccharomyces cerevisiae ?
-
?
S-methyl-L-methionine + L-homocysteine S-methyl-L-methionine more effective methyl donor than S-adenosyl-L-methionine Klebsiella aerogenes ?
-
?