KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.125 | - |
ATP | pH 7.0, 30°C | Saccharomyces cerevisiae | |
0.13 | - |
gamma-S-ATP | pH 7.0, 30°C | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH | the rate-limiting step of the reaction is associated with the chemical process of transfer of the gamma-phosphate of ATP to the sulfinic acid. Two pKapp values of 6.2 and 7.5 of the bell-shaped pH-rate profile correspond to the gamma-phosphate of ATP, and to an acid-base catalyst, respectively | Saccharomyces cerevisiae | peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R | - |
? | |
peroxiredoxin-(S-hydroxy-S-oxocysteine) + gamma-S-ATP + 2 R-SH | - |
Saccharomyces cerevisiae | peroxiredoxin-(S-hydroxycysteine) + ADP + thiophosphate + R-S-S-R | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.016 | - |
gamma-S-ATP | wild-type, pH 7.0, 30°C | Saccharomyces cerevisiae | |
0.03 | - |
ATP | wild-type, pH 7.0, 30°C | Saccharomyces cerevisiae |