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Literature summary for 1.8.4.12 extracted from

  • Li, C.W.; Lee, S.H.; Chieh, P.S.; Lin, C.S.; Wang, Y.C.; Chan, M.T.
    Arabidopsis root-abundant cytosolic methionine sulfoxide reductase B genes MsrB7 and MsrB8 are involved in tolerance to oxidative stress (2012), Plant Cell Physiol., 53, 1707-1719.
    View publication on PubMed
Search for more literature for 1.8.4.12

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Arabidopsis thaliana 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-methionine (R)-sulfoxide + thioredoxin Arabidopsis thaliana
-
 L-methionine + thioredoxin disulfide + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 ecotype Columbia
-

Source Tissue

Source Tissue Comment Organism Textmining
flower low expression Arabidopsis thaliana
-
leaf low expression Arabidopsis thaliana
-
root highest expression in roots Arabidopsis thaliana
-
stem
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-methionine (R)-sulfoxide + thioredoxin
-
 Arabidopsis thaliana L-methionine + thioredoxin disulfide + H2O
-
 ?

Synonyms

Synonyms Comment Organism
methionine sulfoxide reductase B
-
 Arabidopsis thaliana
MsrB7 isoform Arabidopsis thaliana
MsrB8 isoform Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
thioredoxin
-
 Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana isoforms MsrB7 and MsrB8 are induced by oxidative stress up

General Information

General Information Comment Organism
malfunction cytosolic MsrB7 and MsrB8 knockdown lines are sensitive to oxidative stress Arabidopsis thaliana
physiological function isoforms MsrB7 and MsrB8 play an important role in defense against oxidative stress. Transgenic plants overexpressing MsrB7 or MsrB8 are viable and survive after methyl viologen and H2O2 treatment. Arabidopsis plants overexpressing isoforms MsrB7/B8 have shorter roots Arabidopsis thaliana