Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Mycolicibacterium smegmatis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Mycolicibacterium smegmatis | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
13300 | - |
calculated from amino acid sequence | Mycolicibacterium smegmatis |
15000 | - |
SDS-PAGE | Mycolicibacterium smegmatis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycolicibacterium smegmatis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-methionine (R)-sulfoxide + thioredoxin | - |
Mycolicibacterium smegmatis | L-methionine + thioredoxin disulfide + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
methionine sulfoxide reductase B | - |
Mycolicibacterium smegmatis |
MsrB | - |
Mycolicibacterium smegmatis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thioredoxin | - |
Mycolicibacterium smegmatis |
General Information | Comment | Organism |
---|---|---|
malfunction | the msrB mutant MSDELTAmsrB exhibits significantly lower intracellular survival than its wild type counterpart and shows no sensitivity to oxidants in vitro. The msrA/B double mutant (MSDELTAmsrA/B) exhibits a phenotype similar to that of msrA mutant in terms of both intracellular survival and sensitivity to oxidants | Mycolicibacterium smegmatis |
physiological function | MsrB of plays only a limited role in resisting intracellular and in vitro reactive oxygen intermediates | Mycolicibacterium smegmatis |