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Literature summary for 1.8.4.11 extracted from

  • Ogawa, F.; Shimizu, K.; Hara, T.; Muroi, E.; Komura, K.; Takenaka, M.; Hasegawa, M.; Fujimoto, M.; Takehara, K.; Sato, S.
    Autoantibody against one of the antioxidant repair enzymes, methionine sulfoxide reductase A, in systemic sclerosis: association with pulmonary fibrosis and vascular damage (2010), Arch. Dermatol. Res., 302, 27-35.
    View publication on PubMed
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Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UJ68
-
-

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-methionine (S)-sulfoxide + thioredoxin
-
 Homo sapiens L-methionine + thioredoxin disulfide + H2O
-
 ?

Synonyms

Synonyms Comment Organism
methionine sulfoxide reductase A
-
 Homo sapiens
MsrA
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
thioredoxin
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens serum anti-MSRA levels are significantly elevated in systemic sclerosis patients with pulmonary fibrosis, cardiac involvement, or decreased total antioxidant power compared with those without them up