Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | development of a roadmap for rational design of small molecules as potential inhibitors of APS reductase | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
FFQ column chromatography | Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-adenylyl sulfate + thioredoxin | - |
Mycobacterium tuberculosis | AMP + sulfite + thioredoxin disulfide | - |
ir | |
additional information | importance of specific substituent groups for substrate binding | Mycobacterium tuberculosis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
adenosine-5'-phosphosulfate reductase | - |
Mycobacterium tuberculosis |
APS reductase | - |
Mycobacterium tuberculosis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
iron-sulfur centre | iron-sulfur protein | Mycobacterium tuberculosis | |
thioredoxin | - |
Mycobacterium tuberculosis |