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Literature summary for 1.8.1.B1 extracted from

  • Agorio, A.; Chalar, C.; Cardozo, S.; Salinas, G.
    Alternative mRNAs arising from trans-splicing code for mitochondrial and cytosolic variants of Echinococcus granulosus thioredoxin glutathione reductase (2003), J. Biol. Chem., 278, 12920-12928.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
cloning of two trans-spliced mRNA variants that encode thioredoxin glutathione reductases (mitochondrial and cytosolic selenocysteine-containing isoforms) that possess identical glutaredoxin and thioredoxin reductase domains and differ exclusively in their N-termini Echinococcus granulosus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol mitochondrial and cytosolic variants of TGR are generated from a single TGR gene Echinococcus granulosus 5829
-
mitochondrion mitochondrial and cytosolic variants of TGR are generated from a single TGR gene Echinococcus granulosus 5739
-

Organism

Organism UniProt Comment Textmining
Echinococcus granulosus Q869D6
-
-
Echinococcus granulosus Q869D7
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Echinococcus granulosus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,5'-dithiobis(2-nitrobenzoic acid) + NADPH
-
Echinococcus granulosus 2-nitro-5-thiobenzoate + NADP+
-
?
GSSG + NADPH + H+
-
Echinococcus granulosus GSH + NADP+
-
?
thioredoxin disulfide + NADPH + H+
-
Echinococcus granulosus thioredoxin + NADP+
-
?

Synonyms

Synonyms Comment Organism
EgTGR
-
Echinococcus granulosus
thioredoxin glutathione reductase
-
Echinococcus granulosus