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Literature summary for 1.8.1.9 extracted from

  • Kiermayer, C.; Michalke, B.; Schmidt, J.; Brielmeier, M.
    Effect of selenium on thioredoxin reductase activity in Txnrd1 or Txnrd2 hemizygous mice (2007), Biol. Chem., 388, 1091-1097.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
selenium selenoprotein, expression and function depends on adequate supply of selenium Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus homozygous (-/-) knockout of Txnrd1 is embryonically lethal. No major effect of Txnrd1 hemizygosity and/or Se on male fertility and the viability of offspring ?
-
?
additional information Mus musculus homozygous (-/-) knockout of Txnrd2 is embryonically lethal. No major effect of Txnrd2 hemizygosity and/or Se on male fertility and the viability of offspring ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus Q9JLT4
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-
Mus musculus Q9JMH6
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information homozygous (-/-) knockout of Txnrd1 is embryonically lethal. No major effect of Txnrd1 hemizygosity and/or Se on male fertility and the viability of offspring Mus musculus ?
-
?
additional information homozygous (-/-) knockout of Txnrd2 is embryonically lethal. No major effect of Txnrd2 hemizygosity and/or Se on male fertility and the viability of offspring Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
thioredoxin reductase 1
-
Mus musculus
thioredoxin reductase 2
-
Mus musculus
Txnrd1
-
Mus musculus
Txnrd2
-
Mus musculus