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Literature summary for 1.8.1.9 extracted from
- Inhibition of thioredoxin reductase induces apoptosis in neuronal cell lines: role of glutathione and the MKK4/JNK pathway (2007), Biochem. Biophys. Res. Commun., 359, 759-764.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1-chloro-2,4-dinitrobenzene | TrxR inhibition by 1-chloro-2,4-dinitrobenzene results in generation of reactive oxygen species and subsequent activation of stress-inducible kinases without impairment of the cellular antioxidant status or mitochondrial function | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| PC-12 cell | - |
Rattus norvegicus | - |
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Release 2023.1 (January 2023)
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