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Literature summary for 1.8.1.9 extracted from

  • Crosley, L.K.; Meplan, C.; Nicol, F.; Rundloef, A.K.; Arner, E.S.; Hesketh, J.E.; Arthur, J.R.
    Differential regulation of expression of cytosolic and mitochondrial thioredoxin reductase in rat liver and kidney (2007), Arch. Biochem. Biophys., 459, 178-188.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

Metals/Ions Comment Organism Structure
selenium selenoprotein. TrxR1 is more sensitive to Se depletion than TrxR2, greater changes in liver than kidney. There is a prioritisation of TrxR2 over TrxR1 during Se deficiency such that TrxR1 expression is more sensitive to Se supply than TrxR2 but this sensitivity of TrxR1 is not fully accounted for by TrxR1 5' or 3'-untranslated region sequences when assessed using luciferase reporter constructs Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus O89049 male Hooded Lister rats of the Rowett strain
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Rattus norvegicus Rowett O89049 male Hooded Lister rats of the Rowett strain
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Source Tissue

Source Tissue Comment Organism Textmining
kidney
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Rattus norvegicus
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liver
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Rattus norvegicus
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Synonyms

Synonyms Comment Organism
thioredoxin reductase
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Rattus norvegicus
TrxR1
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Rattus norvegicus