Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cd2+ | noncompetitive inhibition with respect to both glutathione disulfide and NADPH | Bos taurus | |
Ni2+ | noncompetitive inhibition with respect to glutathione disulfide and uncompetitive with respect to NADPH | Bos taurus | |
Zn2+ | noncompetitive inhibition with respect to both glutathione disulfide and NADPH | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione disulfide + NADPH + H+ | Bos taurus | - |
glutathione + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
renal cortex | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione disulfide + NADPH + H+ | - |
Bos taurus | glutathione + NADP+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Bos taurus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.027 | - |
pH and temperature not specified in the publication | Bos taurus | Cd2+ | |
0.8 | - |
pH and temperature not specified in the publication | Bos taurus | Ni2+ | |
1 | - |
pH and temperature not specified in the publication | Bos taurus | Zn2+ |