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Literature summary for 1.8.1.7 extracted from

  • Iio, M.; Kawaguchi, H.; Sakota, Y.; Otonari, J.; Nitahara, H.
    Effects of polyphenols, including flavonoids, on glutathione S-transferase and glutathione reductase (1993), Biosci. Biotechnol. Biochem., 57, 1678-1680.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
apigenin flavonone, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
Baicalin slightly, flavone glycoside, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
catechin slightly, catechin, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
chrysin slightly, flavonone, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
epicatechin slightly, catechin, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
epicatechin gallate slightly, catechin, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
epigallocatechin slightly, catechin, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
epigallocatechin gallate catechin, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
fisetin flavonol, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
gallic acid slightly Bos taurus
kaempferol slightly, flavonol, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
morin slightly, flavonol, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
myricetin flavonol, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
quercetin flavonol, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
rutin slightly, flavonol glycoside, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
intestine mucosa Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GSSG + NADPH
-
Bos taurus glutathione + NADP+
-
?

Synonyms

Synonyms Comment Organism
GR
-
Bos taurus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
Bos taurus