Literature summary for 1.8.1.4 extracted from

Brown, A.M.; Gordon, D.; Lee, H.; Wavrant-De Vrieze, F.; Cellini, E.; Bagnoli, S.; Nacmias, B.; Sorbi, S.; Hardy, J.; Blass, J.P.
Testing for linkage and association across the dihydrolipoyl dehydrogenase gene region with Alzheimers disease in three sample populations (2007), Neurochem. Res., 32, 857-869.

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Application

Application	Comment	Organism
medicine	linkage and association analysis of diplotypes in the DLD gene with Alzheimer's from the National Institute of Mental Health-National Cell Repository for Alzheimer's disease and Italian data series, controlling for Gender and ApoE e4 status. Significant evidence of association of DLD with Alzheimer's disease. Combining the linkage and association study results for DLD together, leads to a p-value that is more significant than any of the individual p-value results for DLD. Only with sufficiently large sample sizes it is possible to rule out whether the DLD gene is in fact associated with Alzheimers disease	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Homo sapiens	5739	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
dihydrolipoamide dehydrogenase	-	Homo sapiens
DLD	-	Homo sapiens

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Release 2023.1 (January 2023)