Any feedback?
Literature summary for 1.8.1.14 extracted from
- Borrelia burgdorferi bb0728 encodes a coenzyme A disulphide reductase whose function suggests a role in intracellular redox and the oxidative stress response (2006), Mol. Microbiol., 59, 475-486.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Borreliella burgdorferi |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 50000 | - |
SDS-PAGE | Borreliella burgdorferi |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Borreliella burgdorferi | - |
- |
- |
| Borreliella burgdorferi bb0728 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| T7 antibody agarose column chromatography | Borreliella burgdorferi |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
no activity against oxidized glutathione and thioredoxin | Borreliella burgdorferi |
| 0.38 | - |
using NADPH, aerobic conditions, at 25°C | Borreliella burgdorferi |
| 16.9 | - |
using NADH, aerobic conditions, at 25°C | Borreliella burgdorferi |
| 26.7 | - |
using NADH, anaerobic conditions, at 25°C | Borreliella burgdorferi |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CoA-disulfide + NADH + H+ | - |
Borreliella burgdorferi | CoA + NAD+ | - |
? |  |
| CoA-disulfide + NADH + H+ | - |
Borreliella burgdorferi bb0728 | CoA + NAD+ | - |
? | |
| CoA-disulfide + NADPH + H+ | - |
Borreliella burgdorferi | CoA + NADP+ | - |
? | |
| CoA-disulfide + NADPH + H+ | - |
Borreliella burgdorferi bb0728 | CoA + NADP+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BB0728 | - |
Borreliella burgdorferi |
| CoADR | - |
Borreliella burgdorferi |
| coenzyme A disulphide reductase | - |
Borreliella burgdorferi |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| coenzyme A | - |
Borreliella burgdorferi | |
| NADH | - |
Borreliella burgdorferi | |
| NADPH | - |
Borreliella burgdorferi | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
