Inhibitors | Comment | Organism | Structure |
---|---|---|---|
altenusin | no inhibitory activity on viability of amastigotes | Leishmania amazonensis | |
altenusin | a biphenyl isolated from the endophytic fungus Alternaria sp. | Trypanosoma cruzi | |
alternariol | no inhibitory activity | Trypanosoma cruzi | |
alternariol methyl ether | no inhibitory activity | Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania amazonensis | - |
amastigote | - |
Trypanosoma cruzi | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
trypanothione + 5,5'-dithiobis-(2-nitrobenzoic acid) | - |
Trypanosoma cruzi | trypanothione disulfide + thionitrobenzoate | - |
? | |
trypanothione + 5,5'-dithiobis-(2-nitrobenzoic acid) | - |
Leishmania amazonensis | trypanothione disulfide + thionitrobenzoate | - |
? | |
trypanothione + NADP+ | - |
Trypanosoma cruzi | trypanothione disulfide + NADPH + H+ | - |
? | |
trypanothione + NADP+ | - |
Leishmania amazonensis | trypanothione disulfide + NADPH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
trypanothione reductase | TR | Trypanosoma cruzi |
trypanothione reductase | TR | Leishmania amazonensis |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0043 | - |
- |
Trypanosoma cruzi | altenusin |