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Literature summary for 1.7.1.7 extracted from
- Enzymes of purine metabolism in Mycoplasma mycoides subsp. mycoides (1978), J. Bacteriol., 134, 706-712.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| AMP | 2 mM, 56% inhibition | Mycoplasma mycoides |  |
| ATP | no inhibition without Mg2+, MgATP: no inhibition at 0.010 mM-0.100 mM GMP, strong inhibition below 0.010 mM | Mycoplasma mycoides | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0094 | - |
GMP | - |
Mycoplasma mycoides | |
| 0.01 | - |
NADPH | - |
Mycoplasma mycoides | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mycoplasma mycoides | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.003 | 0.0076 | activity in extracts of cells grown on different media | Mycoplasma mycoides |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADPH + guanosine 5'-phosphate | - |
Mycoplasma mycoides | NADP+ + inosine 5'-phosphate + NH3 | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.3 | - |
- |
Mycoplasma mycoides |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 8.1 | 8.6 | - |
Mycoplasma mycoides |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | specific for | Mycoplasma mycoides | |
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Release 2023.1 (January 2023)
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