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Literature summary for 1.6.99.1 extracted from
- Fixation conditions affect the intensity but not the pattern of NADPH-diaphorase staining as a marker for neuronal nitric oxide synthase in rat olfactory bulb (1994), J. Histochem. Cytochem., 42, 1309-1315.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| alpha-NADPH | diaphorase activity of neuron somata | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
diaphorase activity of nitric oxide synthase | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| olfactory bulb | localized in discrete populations of neuronal somata and in olfactory glomeruli. NADPH-diaphorase activity is due to nitric oxide synthase, the glomerular NADPH-diaphorase activity is not due to nitric oxide synthase | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADH + H+ + acceptor | no activity with beta-NADH | Rattus norvegicus | NAD+ + reduced acceptor | - |
? | |
| NADPH + acceptor | diaphorase activity of neuron somata shows no activity with alpha-NADPH | Rattus norvegicus | NADP+ + reduced acceptor | - |
? | |
| NADPH + acceptor | acceptor: nitroblue tetrazolium hydrochloride | Rattus norvegicus | NADP+ + reduced acceptor | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| nitric oxide synthase | - |
Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | no activity with beta-NADH | Rattus norvegicus | |
| NADPH | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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