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Literature summary for 1.6.5.9 extracted from
- A single external enzyme confers alternative NADH:ubiquinone oxidoreductase activity in Yarrowia lipolytica (1999), J. Cell Sci., 112, 2347-2354.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | not inhibited by piericidin A. Addition of up to 10% (v/v) ethanol has no effect on NADH:NBQ oxidoreductase activity | Yarrowia lipolytica |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.014 | - |
NADH | pH and temperature not specified in the publication | Yarrowia lipolytica |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrial membrane | NDH2 is oriented towards the external face of the mitochondrial inner membrane | Yarrowia lipolytica | 31966 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 65800 | - |
calculated from amino acid sequence | Yarrowia lipolytica |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Yarrowia lipolytica | - |
- |
- |
| Yarrowia lipolytica E 150 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | alternative NADH:ubiquinone oxidoreductase does not pump protons across the inner mitochondrial membrane | Yarrowia lipolytica | ? | - |
? | |
| additional information | alternative NADH:ubiquinone oxidoreductase does not pump protons across the inner mitochondrial membrane | Yarrowia lipolytica E 150 | ? | - |
? | |
| NADH + H+ + 5-nonylubiquinone | - |
Yarrowia lipolytica | NAD+ + 5-nonylubiquinol | - |
? | |
| NADH + H+ + 5-nonylubiquinone | - |
Yarrowia lipolytica E 150 | NAD+ + 5-nonylubiquinol | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alternative NADH:ubiquinone oxidoreductase | - |
Yarrowia lipolytica |
| external NADH:ubiquinone oxidoreductase | - |
Yarrowia lipolytica |
| NDH2 | - |
Yarrowia lipolytica |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Yarrowia lipolytica | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | strains carrying the deletion of NDH2 are completely viable | Yarrowia lipolytica |
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