Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,3-Dimercaptopropanol | - |
Camelus dromedarius | |
5,5'-dithiobis(2-nitrobenzoate) | - |
Camelus dromedarius | |
ADP | 10% inhibition at 0.2 mM | Camelus dromedarius | |
Cu2+ | 25% inhibition at 1 mM | Camelus dromedarius | |
dicoumarol | - |
Camelus dromedarius | |
dithiothreitol | strong competitive inhibition with respect to 9,10-phenanthrenequinone | Camelus dromedarius | |
FAD | 60% inhibition at 0.2 mM | Camelus dromedarius | |
FMN | 40% inhibition at 0.2 mM | Camelus dromedarius | |
NAD+ | 5% inhibition at 0.2 mM | Camelus dromedarius | |
NADP+ | mixed-type inhibition with respect to NADPH, competitive with respect to 9,10-phenanthrenequinone | Camelus dromedarius | |
NEM | - |
Camelus dromedarius | |
warfarin | - |
Camelus dromedarius | |
Zn2+ | 25% inhibition at 1 mM | Camelus dromedarius |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0024 | - |
1,2-naphthoquinone | - |
Camelus dromedarius | |
0.0069 | - |
NADPH | - |
Camelus dromedarius | |
0.013 | - |
oxidized 2,6-dichlorophenolindophenol | - |
Camelus dromedarius | |
0.017 | - |
9,10-phenanthrenequinone | - |
Camelus dromedarius | |
0.065 | - |
1,4-benzoquinone | - |
Camelus dromedarius | |
0.26 | - |
1,4-Naphthoquinone | - |
Camelus dromedarius |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Camelus dromedarius | - |
camel | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
NADPH + H+ + 2 quinone = NADP+ + 2 semiquinone | reaction with 9,10-phenanthrenequinone and NADPH proceeds through a ping-pong mechanism | Camelus dromedarius |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lens | - |
Camelus dromedarius | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,2-naphthoquinone + NADPH | - |
Camelus dromedarius | 1,2-naphthoquinol + NADP+ | - |
? | |
1,4-benzoquinone + NADPH | - |
Camelus dromedarius | 1,4-benzosemiquinone + NADP+ | - |
? | |
1,4-naphthoquinone + NADPH + H+ | - |
Camelus dromedarius | 1,4-naphthosemiquinone + NADP+ | - |
? | |
9,10-phenanthrenequinone + NADPH | best substrate | Camelus dromedarius | 9,10-phenanthrenesemiquinone + NADP+ | - |
? | |
NADPH + H+ + oxidized 2,6-dichlorophenolindophenol | - |
Camelus dromedarius | NADP+ + reduced 2,6-dichlorophenolindophenol | - |
? |