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Literature summary for 1.6.5.10 extracted from

  • Diatchuk, V.; Lotan, O.; Koshkin, V.; Wikstroem, P.; Pick, E.
    Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds (1997), J. Biol. Chem., 272, 13292-13301.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
lithiumdodecylsulfate
-
Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expression of p47-phox and p67-phox in Sf9 cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
4-(2-aminoethyl)benzenesulfonylfluoride
-
Cavia porcellus
4-(2-aminoethyl)benzenesulfonylfluoride 0.206 mM, 50% inhibition, noncompetitive vs. NADPH, competitive vs. p47-phox in the concentration range of 0.5-2.0 mM Homo sapiens
4-(amidino)benzenesulfonylfluoride 1.49 mM, 50% inhibition Homo sapiens

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
cytochrome b558 from neutrophils Homo sapiens