Inhibitors | Comment | Organism | Structure |
---|---|---|---|
fulvene-5 | potent inhibitor of NADPH oxidase 4 | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain endothelial cell | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
NADPH oxidase 4 | - |
Mus musculus |
Nox4 | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | Nox4 is downregulated in angiopoietin 2 heterozygous cells | down |
General Information | Comment | Organism |
---|---|---|
malfunction | lentiviral silencing of Nox4 in an Ang2-sufficient bEnd cell line decreases Ang2 mRNA levels and greatly impairs hemangioma growth in vivo | Mus musculus |
physiological function | Nox4 is a critical regulator of hemangioma growth | Mus musculus |