Inhibitors | Comment | Organism | Structure |
---|---|---|---|
apocynin | inhibitor of NAD(P)H oxidase activation | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mus musculus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
myocardium | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + H+ + O2 | - |
Mus musculus | NADP+ + H2O2 | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Mus musculus | |
heme | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | NAD(P)H oxidase activity is not increased in mice from the normal diet plus myocardial infarction group | additional information |
Mus musculus | NAD(P)H oxidase activity is increased in noninfarcted left ventricular tissues from mice in the high fat diet plus myocardial infarction group | up |
General Information | Comment | Organism |
---|---|---|
physiological function | increased myocardial NAD(P)H oxidase-derived superoxide causes the exacerbation of postinfarct heart failure in type 2 diabetes | Mus musculus |