Literature summary for 1.6.3.1 extracted from

Egan, M.J.; Wang, Z.Y.; Jones, M.A.; Smirnoff, N.; Talbot, N.J.
Generation of reactive oxygen species by fungal NADPH oxidases is required for rice blast disease (2007), Proc. Natl. Acad. Sci. USA, 104, 11772-11777.

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Application

Application	Comment	Organism
agriculture	both genes coding for NAD(P)H oxidases, Nox1 and Nox2, are independently required for pathogenicity of Magnaporthe grisea. Mutants lacking either nox1 or nox2 are incapable of causing plant disease because of unability to bring about appresorium-mediated cuticle penetration	Pyricularia grisea

Protein Variants

Protein Variants	Comment	Organism
additional information	both genes coding for NAD(P)H oxidases, Nox1 and Nox2, are independently required for pathogenicity. Mutants lacking either nox1 or nox2 are incapable of causing plant disease because of unability to bring about appresorium-mediated cuticle penetration. A nox1nox2 double mutant shows significant increase in superoxide production at the hyphal tips	Pyricularia grisea

Organism

Organism	UniProt	Comment	Textmining
Pyricularia grisea	-	rice pathogen, which undergoes an oxidative blast of its own during plant infection	-

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Release 2023.1 (January 2023)