Literature summary for 1.6.3.1 extracted from

Biswas, S.; Gupta, M.K.; Chattopadhyay, D.; Mukhopadhyay, C.K.
Insulin-induced activation of hypoxia inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase (2006), Am. J. Physiol. Heart Circ. Physiol., 292, 758-766.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in H9C2 cell	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
apocynin	enzyme inhibitor, pretreatment of cells completely blocks insulin-stimulated activation of hypoxia-inducible factor 1	Homo sapiens
diphenylene iodinium chloride	enzyme inhibitor, pretreatment of cells completely blocks insulin-stimulated activation of hypoxia-inducible factor 1	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	essential role of enzyme-generated reactive oxigen species in insulin-stimulated activation of hypoxia-inducible factor 1	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	essential role of enzyme-generated reactive oxigen species in insulin-stimulated activation of hypoxia-inducible factor 1	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)