Activating Compound | Comment | Organism | Structure |
---|---|---|---|
8-bromo-cAMP | can replace for thyrotropin | Sus scrofa | |
forskolin | can replace thyrotropin | Sus scrofa | |
additional information | upregulated by agents activationg cAMP pathway | Sus scrofa | |
thyrotropin | almost no activity in cells grown without | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.015 | - |
NADPH | pH 7.2, 30°C, 1.5 mM Ca2+ | Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | regulates enzyme activity | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD(P)H + H+ + O2 | Sus scrofa | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | NAD(P)+ + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
thyroid gland | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD(P)H + H+ + O2 | - |
Sus scrofa | NAD(P)+ + H2O2 | - |
? | |
NAD(P)H + H+ + O2 | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | Sus scrofa | NAD(P)+ + H2O2 | - |
? |