Activating Compound | Comment | Organism | Structure |
---|---|---|---|
arachidonic acid | maximal enzyme activity in the presence of 0.25-0.35 mM, inhibition above | Bos taurus | |
GTP-gammaS | optimal concentration approx. 0.015 mM | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
lucensomycin | 0.02 mM, 50% inhibition | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Bos taurus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + O2 | Bos taurus | - |
NADP+ + O2- | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
multienzyme complex | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | resting neutrophils | Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.015 | - |
activity in membranes after 1 h at 25°C | Bos taurus |
0.033 | - |
activity in freshly prepared membranes at 25°C | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + O2 | - |
Bos taurus | NADP+ + O2- | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
activity in membranes, approx. 50% activity are lost after 1 h, freeze/thawing accelerates inactivation, loss of 90% activity after 1 h | Bos taurus |