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Literature summary for 1.5.5.1 extracted from

  • Goodman, S.I.; Axtell, K.M.; Bindoff, L.A.; Beard, S.E.; Gill, R.E.; Frerman, F.E.
    Molecular cloning and expression of a cDNA encoding human electron transfer flavoprotein-ubiquinone oxidoreductase (1994), Eur. J. Biochem., 219, 277-286.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Saccharomyces cerevisiae, the enzyme is synthesized as a 67000 Da precursor which is targeted to mitochondria and processed in a single step to a 64000 Da mature form Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
p-chloromercuribenzoate complete inhibition of ubiquinone reductase activity, 70% inhibition of disproportion activity Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
64000
-
x * 64000, mature enzyme, immunoblotting Homo sapiens
67000
-
x * 67000, immunoprecipitation after in vitro translation, deduced from nucletide sequence Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.139
-
ubiquinone reduction Homo sapiens
1.3
-
disproportionation of semiquinone electron-transferring flavoprotein Homo sapiens

Subunits

Subunits Comment Organism
? x * 67000, immunoprecipitation after in vitro translation, deduced from nucletide sequence Homo sapiens
? x * 64000, mature enzyme, immunoblotting Homo sapiens