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Literature summary for 1.5.1.42 extracted from
- Flavin mononucleotide reductase of luminous bacteria (1975), Mol. Cell. Biochem., 6, 53-64.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| antimycin A | 0.05 mM, 50% inhibition | Vibrio harveyi |  |
| additional information | no inhibition by 0.01 mM 2,4-dinitrophenol, 0.2 mM dicoumarol, 0.1 mM rotenone | Vibrio harveyi |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 23000 | - |
gel filtration | Vibrio harveyi |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| FMN + NADH + H+ | Vibrio harveyi | - |
FMNH2 + NAD+ | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Vibrio harveyi | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Vibrio harveyi |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
purity was too low to permit estimation of specific activity | Vibrio harveyi |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| FAD + NADH + H+ | activity with FADH2 and NAD+ is 5% of the activity with FMNH2 and NAD+ | Vibrio harveyi | FADH2 + NAD+ | - |
? | |
| FMN + NADH + H+ | - |
Vibrio harveyi | FMNH2 + NAD+ | - |
? | |
| FMN + NADH + H+ | activity with NADP+ and FMNH2 is only 10% of the activity with FMNH2 and NAD+ | Vibrio harveyi | FMNH2 + NAD+ | - |
? | |
| FMN + NADPH + H+ | activity with NADP+ and FMNH2 is only 10% of the activity with FMNH2 and NAD+ | Vibrio harveyi | FMNH2 + NADP+ | - |
? | |
| additional information | activity with FAD and NADPH is 0.5% of the activity with FMNH2 and NAD+ | Vibrio harveyi | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NADH:FMN oxidoreductase (flavin reductase) | - |
Vibrio harveyi |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 20 | - |
assay at | Vibrio harveyi |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
assay at | Vibrio harveyi |
| 8.5 | - |
- |
Vibrio harveyi |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5 | 10 | bimodal, pH 5: 90% of maximal activity, pH 6.5: about 50% of maximal activity, pH 10: about 70% of maximal activity | Vibrio harveyi |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | activity with NADPH and FMNH2 is only 10% of the activity with FMNH2 and NAD+ | Vibrio harveyi | |
| NADPH | activity with NADPH and FMNH2 is only 10% of the activity with FMNH2 and NAD+ | Vibrio harveyi | |
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Release 2023.1 (January 2023)
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