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Literature summary for 1.5.1.3 extracted from

  • Stanislawska-Sachadyn, A.; Brown, K.S.; Mitchell, L.E.; Woodside, J.V.; Young, I.S.; Scott, J.M.; Murray, L.; Boreham, C.A.; McNulty, H.; Strain, J.J.; Whitehead, A.S.
    An insertion/deletion polymorphism of the dihydrofolate reductase (DHFR) gene is associated with serum and red blood cell folate concentrations in women (2008), Hum. Genet., 123, 289-295.
    View publication on PubMed

Application

Application Comment Organism
medicine analysis of the impact of the dihydrofolate reductase c.86 + 60_78 insertion/deletion polymorphism on folate and homocysteine concentrations. Among men the polymorphism is not signficantly associated with serum or red blood cell folate concentrations, or with homocysteine concentrations. Among women the polymorphis mexplains 2% of the variation in red blood cell folate levels and 5% of the variation in serum folate levels, but does not appear to have an independent effect on homocysteine Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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c.86 + 60_78 insertion/deletion polymorphism is associated with serum and red blood cell folate concentrations in women
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Source Tissue

Source Tissue Comment Organism Textmining
blood
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Homo sapiens
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serum
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Homo sapiens
-