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Literature summary for 1.5.1.3 extracted from

  • Schnell, J.R.; Dyson, H.J.; Wright, P.E.
    Structure, dynamics, and catalytic function of dihydrofolate reductase (2004), Annu. Rev. Biophys. Biomol. Struct., 33, 119-140.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
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Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P0ABQ4
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7,8-dihydrofolate + NADPH kinetic mechanism Escherichia coli 5,6,7,8-tetrahydrofolate + NADP+
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?

Synonyms

Synonyms Comment Organism
DHFR
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Escherichia coli

Cofactor

Cofactor Comment Organism Structure
NADPH
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Escherichia coli