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Literature summary for 1.5.1.3 extracted from

  • Dann, J.G.; Harding, N.G.L.; Newbold, P.C.H.; Whiteley, J.M.
    Single-step purification of dihydrofolate reductases on pteridine matrices (1972), Biochem. J., 127, 28P-29P.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.5.1.3

Inhibitors

Inhibitors Comment Organism Structure
folate NADPH stabilizes against intracellular inactivation via folate Lacticaseibacillus casei
methotrexate
-
 Lacticaseibacillus casei

Organism

Organism UniProt Comment Textmining
Lacticaseibacillus casei
-
-
-

Purification (Commentary)

Purification (Comment) Organism
single-step purification on pteridine matrices Lacticaseibacillus casei

Renatured (Commentary)

Renatured (Comment) Organism
sodium docecyl sulfate causes irreversible inactivation Lacticaseibacillus casei

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7,8-dihydrofolate + NADPH
-
 Lacticaseibacillus casei 5,6,7,8-tetrahydrofolate + NADP+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Lacticaseibacillus casei