Literature summary for 1.5.1.2 extracted from

Hayward, D.C.; Delaney, S.J.; Campbell, H.D.; Ghysen, A.; Benzer, S.; Kasprzak, A.B.; Cotsell, J.N.; Young, I.G.; Miklos, G.L.G.
The sluggish-A gene of Drosophila melanogaster is expressed in the nervous system and encodes proline oxidase, a mitochondrial enzyme involved in glutamate biosynthesis (1993), Proc. Natl. Acad. Sci. USA, 90, 2979-2983.

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KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
50	-	L-proline	-	Drosophila melanogaster

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Drosophila melanogaster	-	wild type and mutant flies	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
nervous system	-	Drosophila melanogaster	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	specific activity in various mutant flies	Drosophila melanogaster

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-proline + NAD(P)+	-	Drosophila melanogaster	1-pyrroline-5-carboxylate + NAD(P)H + H+	-	r

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Release 2023.1 (January 2023)