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Literature summary for 1.5.1.15 extracted from

  • Patel, H.; Christensen, K.E.; Mejia, N.; Mackenzie, R.E.
    Mammalian mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase (2002), Arch. Biochem. Biophys., 403, 145-148.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
isolation of cDNA and the gene encoding the murine cytoplasmic methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase (DCS) Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-5,10-methenyl-tetrahydrofolate + NADH Drosophila melanogaster
-
L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH Mus musculus
-
L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH Homo sapiens
-
L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methylenetetrahydrofolate + NAD+ Drosophila melanogaster
-
5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+ Mus musculus
-
5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+ Homo sapiens
-
5,10-methenyl-tetrahydrofolate + NADH
-
r

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-
Homo sapiens
-
human
-
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-5,10-methenyl-tetrahydrofolate + NADH
-
Drosophila melanogaster L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH
-
Mus musculus L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH
-
Homo sapiens L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methylenetetrahydrofolate + NAD+
-
Drosophila melanogaster 5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+
-
Mus musculus 5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+
-
Homo sapiens 5,10-methenyl-tetrahydrofolate + NADH
-
r

Synonyms

Synonyms Comment Organism
methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase
-
Mus musculus
methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase
-
Homo sapiens