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Literature summary for 1.5.1.15 extracted from

  • Tremblay, G.B.; Sohi, S.S.; Retnakaran, A.; Mackenzie, R.E.
    NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is targeted to the cytoplasm in insect cell lines (1995), FEBS Lett., 368, 177-182.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Mus musculus
-
Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Drosophila melanogaster 5737
-
cytoplasm
-
Mus musculus 5737
-
cytoplasm
-
Homo sapiens 5737
-
cytoplasm
-
Spodoptera frugiperda 5737
-
mitochondrion
-
Drosophila melanogaster 5739
-
mitochondrion
-
Mus musculus 5739
-
mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-5,10-methenyl-tetrahydrofolate + NADH Drosophila melanogaster
-
L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH Mus musculus
-
L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH Homo sapiens
-
L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH Spodoptera frugiperda
-
L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH Choristoneura fumiferana
-
L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH Antheraea eucalypti
-
L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH Malacosoma disstria
-
L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methylenetetrahydrofolate + NAD+ Drosophila melanogaster
-
5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+ Mus musculus
-
5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+ Homo sapiens
-
5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+ Spodoptera frugiperda
-
5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+ Choristoneura fumiferana
-
5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+ Antheraea eucalypti
-
5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+ Malacosoma disstria
-
5,10-methenyl-tetrahydrofolate + NADH
-
r

Organism

Organism UniProt Comment Textmining
Antheraea eucalypti
-
moth, cell line (ATCC)CCL 80
-
Choristoneura fumiferana
-
spruce budworm, cell lines IPRI CF1, IPRI CF16T, IPRI CF124T, FPMI-CF-70, FPMI-CF-27 and FPMI-34
-
Drosophila melanogaster
-
fruit fly, cell line S3
-
Homo sapiens
-
-
-
Malacosoma disstria
-
forest tent caterpillar, cell line IPRI-MD-66
-
Mus musculus
-
-
-
Spodoptera frugiperda
-
fall armyworm, cell line Sf9
-

Purification (Commentary)

Purification (Comment) Organism
-
Spodoptera frugiperda

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
Drosophila melanogaster
-
embryo
-
Mus musculus
-
fat body
-
Choristoneura fumiferana
-
hemocyte
-
Malacosoma disstria
-
integument
-
Choristoneura fumiferana
-
larva neonate Choristoneura fumiferana
-
ovary
-
Choristoneura fumiferana
-
ovary pupal ovaries Antheraea eucalypti
-
testis
-
Choristoneura fumiferana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-5,10-methenyl-tetrahydrofolate + NADH
-
Drosophila melanogaster L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH
-
Mus musculus L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH
-
Homo sapiens L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH
-
Spodoptera frugiperda L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH
-
Choristoneura fumiferana L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH
-
Antheraea eucalypti L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methenyl-tetrahydrofolate + NADH
-
Malacosoma disstria L-5,10-methylenetetrahydrofolate + NAD+
-
r
L-5,10-methylenetetrahydrofolate + NAD+
-
Drosophila melanogaster 5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+
-
Mus musculus 5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+
-
Homo sapiens 5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+
-
Spodoptera frugiperda 5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+
-
Choristoneura fumiferana 5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+
-
Antheraea eucalypti 5,10-methenyl-tetrahydrofolate + NADH
-
r
L-5,10-methylenetetrahydrofolate + NAD+
-
Malacosoma disstria 5,10-methenyl-tetrahydrofolate + NADH
-
r

Synonyms

Synonyms Comment Organism
NMDMC
-
Drosophila melanogaster
NMDMC
-
Mus musculus