Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CO2 | product inhibition | Gallus gallus | |
Glycine methyl ester | - |
Gallus gallus | |
Modified H-protein | lipoic acid prosthetic group and cysteinyl residues modified with N-ethylmaleimide | Gallus gallus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0034 | - |
glycine | - |
Gallus gallus | |
5.8 | - |
glycine | - |
Gallus gallus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycine + lipoylprotein | Gallus gallus | lipoyl protein: H-protein, lipoamide can also act as acceptor | S-aminomethyldihydrolipoylprotein + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
glycine + [glycine-cleavage complex H protein]-N6-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N6-dihydrolipoyl-L-lysine + CO2 | mechanism | Gallus gallus | |
glycine + [glycine-cleavage complex H protein]-N6-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N6-dihydrolipoyl-L-lysine + CO2 | sequential random bi bi mechanism in which no abortive dead end complex is formed | Gallus gallus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Gallus gallus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycine + lipoylprotein | lipoyl protein: H-protein, lipoamide can also act as acceptor | Gallus gallus | S-aminomethyldihydrolipoylprotein + CO2 | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.1 | - |
glycine + lipoylprotein | Gallus gallus |