Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ethanol | 2fold activation in the presence of ethanol | Octopus vulgaris |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
iodoacetate | 68% inhibition at 0.1 mM | Octopus vulgaris | |
o-Iodosobenzoate | 32% inhibition at 0.1 mM | Octopus vulgaris | |
p-chloromercuribenzoate | 74% inhibition at 0.01 mM | Octopus vulgaris | |
urethane | 31% inhibition at 10 mM | Octopus vulgaris | |
Veronal | 60% inhibition at 8 mM | Octopus vulgaris |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
4.5 | - |
D-Aspartate | - |
Octopus vulgaris | |
8 | - |
D-glutamate | - |
Octopus vulgaris |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-aspartate + H2O + O2 | Octopus vulgaris | 70% higher activity with pure oxygen than in air | oxaloacetate + NH3 + H2O2 | - |
? | |
D-aspartate + H2O + O2 | Octopus vulgaris | poorer substrate than D-glutamate | oxaloacetate + NH3 + H2O2 | - |
? | |
D-glutamate + H2O + O2 | Octopus vulgaris | better substrate than D-aspartate | 2-oxoglutarate + NH3 + H2O2 | - |
? | |
D-glutamate + H2O + O2 | Octopus vulgaris | highly specific, 70% higher activity with pure oxygen than in air | 2-oxoglutarate + NH3 + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Octopus vulgaris | - |
- |
- |
Purification (Comment) | Organism |
---|---|
to homogeneity, precipitation techniques, calcium phosphate gel treatment | Octopus vulgaris |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hepatopancreas | - |
Octopus vulgaris | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-aspartate + H2O + O2 | 70% higher activity with pure oxygen than in air | Octopus vulgaris | oxaloacetate + NH3 + H2O2 | - |
? | |
D-aspartate + H2O + O2 | poorer substrate than D-glutamate | Octopus vulgaris | oxaloacetate + NH3 + H2O2 | - |
? | |
D-glutamate + H2O + O2 | better substrate than D-aspartate | Octopus vulgaris | 2-oxoglutarate + NH3 + H2O2 | - |
? | |
D-glutamate + H2O + O2 | highly specific, 70% higher activity with pure oxygen than in air | Octopus vulgaris | 2-oxoglutarate + NH3 + H2O2 | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.1 | 8.3 | - |
Octopus vulgaris |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | cannot be replaced by FMN | Octopus vulgaris |